diff --git a/tests/benchmark/compute/instruction/test_memory.py b/tests/benchmark/compute/instruction/test_memory.py
index e4a9decb8e..b737fe1ae7 100644
--- a/tests/benchmark/compute/instruction/test_memory.py
+++ b/tests/benchmark/compute/instruction/test_memory.py
@@ -111,3 +111,72 @@ def test_mcopy(
             attack_block=attack_block, cleanup=mem_touch
         ),
     )
+
+
+@pytest.mark.parametrize("opcode", [Op.MLOAD, Op.MSTORE, Op.MSTORE8])
+@pytest.mark.parametrize(
+    "memory_layout",
+    [
+        pytest.param("sequential", id="sequential"),
+        pytest.param("sparse", id="sparse"),
+        pytest.param("overlapping", id="overlapping"),
+    ],
+)
+@pytest.mark.parametrize("overwrite_existing", [True, False])
+def test_memory_layout_access(
+    benchmark_test: BenchmarkTestFiller,
+    opcode: Op,
+    memory_layout: str,
+    overwrite_existing: bool,
+) -> None:
+    """
+    Benchmark memory access with custom layouts and overwriting scenarios.
+
+    Variants:
+    - memory_layout: Memory initialization pattern
+      (sequential=stride 32, sparse=stride 1000, overlapping=stride 16)
+    - overwrite_existing: Pre-write to the access offset before operations
+    - opcode: Memory operation (MLOAD, MSTORE, MSTORE8)
+    """
+    setup = Bytecode()
+
+    # Initialize memory with pattern
+    if memory_layout == "sequential":
+        # Write sequential 32-byte words: 0, 32, 64, 96, 128...
+        for i in range(10):
+            setup += Op.MSTORE(i * 32, i)
+        access_offset = 64  # Access middle of initialized memory
+    elif memory_layout == "sparse":
+        # Write to sparse locations: 0, 1000, 2000, 3000...
+        for i in range(10):
+            setup += Op.MSTORE(i * 1000, i)
+        access_offset = 2000  # Access sparse location
+    elif memory_layout == "overlapping":
+        # Overlapping 32-byte words (16-byte stride)
+        for i in range(20):
+            setup += Op.MSTORE(i * 16, i)
+        access_offset = 48  # Access overlapping region
+
+    # Overwrite pattern: pre-write to the access offset
+    if overwrite_existing:
+        if opcode == Op.MSTORE8:
+            setup += Op.MSTORE8(access_offset, 0xEF)
+        else:
+            setup += Op.MSTORE(access_offset, 0xDEADBEEF)
+
+    # Prepare stack for operation
+    setup += Op.PUSH1(42) + Op.PUSH2(access_offset)
+
+    # Attack block performs the memory operation
+    attack_block = (
+        Op.POP(Op.MLOAD(Op.DUP1))
+        if opcode == Op.MLOAD
+        else opcode(Op.DUP2, Op.DUP2)
+    )
+
+    benchmark_test(
+        code_generator=JumpLoopGenerator(
+            setup=setup,
+            attack_block=attack_block,
+        ),
+    )