When constructing a new UsbBus with usb-device 0.2.9 (atsamd21g implementation running on a SAMD21G17D without compile-time optimizations) fatal CPU errors can arise on the target device.
Likely this is due to stack overflow issues as it occurs while allocating a largish chunk of memory and may be a change more for the atsamd-hal/thumbv6m code that implements the UsbBus, but should check.
Some error and stack trace info:
UsbBusATSAMD21G17DDebugInfo.txt