Name : Parameswar
Role : Scientist (Bioinformatics)
Focus : NGS • Multi-Omics • CADD
Domains : Oncology • Cardio • Neurodegeneration
Mission : Reproducible science at scale
Status : Building pipelines that outlast the grant 🧬I work at the intersection of algorithms and biology — building robust, scalable pipelines that transform raw sequencing data into clinical and therapeutic insight. From riverine metagenomics to cancer genomics to in silico drug design, I chase the signal in biological noise.
Omics & Sequencing
Drug Discovery & Simulation
Pipelines & Infrastructure
[ACTIVE] Reproducible Nextflow/nf-core workflows for WES • WGS • WGBS • RNA-Seq • Metagenomics
[ACTIVE] CADD + Molecular Simulation integration for drug discovery pipelines
[ACTIVE] Containerizing bioinformatics tools for portable, zero-setup reproducibility
[ACTIVE] Multi-omics integration: Oncology • Cardiovascular • Neurodegeneration
[CONCEPT] Automated annotation and clinical interpretation layer for somatic variant pipelines
| Domain | Omics Applied | Output |
|---|---|---|
| 🎗️ Oncology | WES · WGS · RNA-Seq · WGBS | Somatic variants · CNV · DMRs · DEGs |
| ❤️ Cardiovascular | Multi-omics | Pathway integration · Biomarkers |
| 🧠 Neurodegeneration | Genomics · Transcriptomics | Variant annotation · Expression profiling |
| 🌊 Riverine Metagenomics | Shotgun · Targeted | Microbial ecology · Functional annotation |
Open to collaborations on reproducible pipelines, multi-omics integration, and open science.
Empowering Life Sciences with Scalable, Reproducible, and Automated
Bioinformatics Solutions — one pipeline at a time. 🧬